3D images
Composition and form of release
in a blister pack 1 pc.; in a pack of cardboard 1 or 2 packs or in a jar 1 or 2 pcs.; in a pack of cardboard 1 bank.
pharmachologic effect
pharmachologic effect- contraceptive, antiprogestogen.Pharmacodynamics
Mifepristone is a synthetic steroid antiprogestogen (blocks the action of progesterone at the receptor level), does not have gestagenic activity. Marked antagonism with GCS (due to competition at the level of communication with receptors).
Depending on the phase of the menstrual cycle, it causes an increase in the contractility of the myometrium, stimulating the release of interleukin-8 in choriodecidual cells, increasing the sensitivity of the myometrium to PG. As a result of the action of the drug, desquamation of the decidual membrane and the excretion of the fetal egg occur. It causes inhibition of ovulation, changes in the endometrium and prevents the implantation of a fertilized egg.
Pharmacokinetics
After a single oral administration, C max is reached after 1.3 hours. The absolute bioavailability is 69%. In blood plasma, mifepristone is 98% protein bound: albumin and acidic α 1 -glycoprotein.
After the distribution phase, excretion is slow at first, the concentration decreases by a factor of 2 between 12-72 hours, then more rapidly. T 1/2 is 18 hours.
Indications for Genale ®
Emergency (postcoital) contraception within 72 hours after intercourse without prior use of contraceptives or methods, as well as in case of unsuccessful use of them (including an error in the application of the calendar method, unsuccessful interruption of sexual intercourse, rupture or slipping of the condom).
Contraindications
a history of hypersensitivity to mifepristone and / or auxiliary components;
adrenal insufficiency;
acute or chronic renal and / or liver failure;
long-term therapy with glucocorticosteroids;
porphyria;
violations of hemostasis (including previous treatment with anticoagulants);
the presence of severe extragenital pathology;
pregnancy;
lactation period.
Use during pregnancy and lactation
The drug should not be used during pregnancy. Breast-feeding should be discontinued for 14 days after taking the drug.
Side effects
Bloody discharge from the genital tract, discomfort and pain in the lower abdomen; exacerbation of inflammatory diseases of the uterus and appendages; weakness, headache, nausea, vomiting, diarrhea, dizziness, hyperthermia, urticaria.
Interaction
The use of NSAIDs should be avoided for 8-12 days after taking the drug.
Dosage and administration
inside. 1 tab. 2 hours before or 2 hours after a meal (in the next 72 hours after unprotected intercourse), regardless of the phase of the menstrual cycle.
Overdose
Symptoms: in cases of drug overdose, adrenal insufficiency may occur.
Precautionary measures
The drug does not protect against sexually transmitted diseases and AIDS; it is not recommended to use the drug as a planned, permanent contraception after each sexual intercourse, as well as monthly.
After use as postcoital contraception and until the end of the current menstrual cycle, subsequent sexual intercourse without the use of contraceptives is not recommended. With further sexual intercourse, a barrier method of contraception should be used.
The 10 mg dose of the drug is not sufficient to induce an abortion, so a highly sensitive pregnancy test should be performed before further use to ensure that this drug is used only in the absence of pregnancy. In the event of pregnancy, despite the use of the drug, it is recommended to terminate it with a medical or surgical method. If the patient decides to continue the pregnancy, it is impossible to completely eliminate the risk to the health of the unborn child.
Influence on the ability to drive a car or perform work that requires an increased speed of physical and mental reactions. The effect of the drug on the ability to drive a car and work with mechanisms was not noted.
Terms of dispensing from pharmacies
On prescription.
Storage conditions of the drug Zhenale ®
In a place protected from light, at a temperature not exceeding 25 ° C.Keep out of the reach of children.
Shelf life of the drug Genale ®
3 years.Do not use after the expiry date stated on the packaging.
Synonyms of nosological groups
| Category ICD-10 | Synonyms of diseases according to ICD-10 |
|---|---|
| Z30 Surveillance of contraceptive use | Hormonal contraception |
| Contraception | |
| Contraception intrauterine | |
| Local contraception | |
| Oral contraception | |
| Contraception in women with androgenization phenomena | |
| Local contraception | |
| Insertion and removal of the intrauterine device | |
| Z30.0 General advice and advice on contraception | safe sex |
| intrauterine contraception | |
| Contraception | |
| Contraception intrauterine | |
| Contraception in adolescents | |
| oral contraception | |
| Oral contraception during lactation and when estrogens are contraindicated | |
| Postcoital contraception | |
| Pregnancy protection | |
| Prevention of pregnancy (contraception) | |
| Prevention of unwanted pregnancy | |
| emergency contraception | |
| Episodic contraception |
Genale tablets - modern postcoital contraceptive drug intended for oral administration. The main indications for use - emergency contraception within 72 hours of unprotected intercourse or treatment of uterine leiomyoma. IN extreme cases with the help of this drug, uterine pregnancy is terminated at very early stages (up to 6 weeks).
Genale: composition, form of release and packaging of the drug
The drug is available in the form of round biconvex tablets of yellow color, sometimes with a greenish tint.
One tablet contains 10 mg, as well as auxiliary substances - 22 mg of potato starch, 123.4 mg of lactose monohydrate, 6 mg of povidone K25, 5 mg of sodium carboxymethyl starch and 1.6 mg of magnesium stearate.
Packed one tablet in blister packs (in a pack of 1 or 2 tablets) or in orange glass jars (1 or 2 tablets in a jar). Sold in cardboard boxes.
Pharmacodynamics
The active substance of the tablets Zhenale - mifepristone, an antiprogestogenic steroid synthetic origin, capable of blocking the interaction of progesterone and progestogen receptors.
Mifepristone to varying degrees increases myometrial contractions and stimulates the release of interleukin-8 in choriodecidual cells (the degree depends on the menstrual phase), resulting in desquamation (in other words, scaly peeling of the epithelium layer) of the decidua. Along with peeling, rejection of the fetal egg also occurs. Also, due to desquamation when taking the drug, ovulation is impossible.
Pharmacokinetics
Already 1.5 hours after oral administration, the drug reaches maximum blood concentration. The drug is bioavailable by 69-70%. 99.2% of mifepristone binds to plasma proteins. The half-life is 17 hours. The withdrawal of funds occurs in two stages, at first rather slowly, and after 12-72 hours much faster.
Indications for use
emergency contraception(post-coital, i.e. already after intercourse) within 72 hours after unprotected sex, as well as if contraception was unsuccessful (for example, a condom rupture, unsuccessful interruption of intercourse, a calendar error, etc.) . For this purpose, a single dose of tablets containing 10 mg of mifepristone will suffice.
For the treatment of uterine leiomyoma (benign tumor), you need to take 50 mg or more (as prescribed by your doctor).
In rare cases, the drug is used to terminate a pregnancy in the early stages (up to six weeks) or in preparation for childbirth.
Tablets Genale: instructions for use
Contraindications
Emergency contraception Genale contraindicated in case if you have hypersensitivity to mifepristone, adrenal insufficiency, if you long time were treated with glucocorticoids. Also, tablets should not be taken if there is chronic liver and / or kidney failure, scars on the uterus, porphyria, any inflammation of the genital organs, impaired hemostasis, severe extragenital pathology, anemia.
When a pregnancy is terminated early term it is forbidden to take Genale if there is a suspicion of ectopic pregnancy, or if the period of delay is more than 42 days, and also if there is uterine fibroids. It is strictly forbidden to take the drug during pregnancy unconfirmed by clinical studies.
In the treatment of uterine leiomyoma Genale should not be taken if the size of the leiomyoma is more than 12 weeks of gestation, if there is an ovarian tumor or hyperplasia, endometrium, pregnancy or lactation, as well as with a submucous location of myomatous nodes.
Genale tablets: side effects
For side effects after taking contraception, weakness, headache, discomfort in the lower abdomen, nausea and vomiting, hyperthermia, diarrhea, skin rashes, menstrual irregularities can be attributed, bloody issues.
Additionally, effects associated with termination of pregnancy can be noted: bleeding, inflammation of the uterus or appendages, pain in the lower abdomen, exacerbation of inflammation urinary tract or uterus.
drug overdose
Overdose there are symptoms of adrenal insufficiency. If you suspect that you have taken a large dose of the drug, visit your doctor as soon as possible.
Genale: analogues of the drug
- There are structural analogues, the active substance of which is also mifepristone, for example, Agesta, or (there is also), and a number of drugs with a similar name: Mifeprex, Mifolian, etc.
- There are also analogues for pharmacological group. These include tools such as Postinor, Gynecotex and others.
Most often, girls in a pharmacy have a controversial issue: buy Genale or Postinor? To answer it, you need to compare both drugs in more detail.
The active substance of Postinor is levonorgestrel. In fact, Postinor also refers to postcoital contraception and has a similar principle of action, the instructions for using these drugs are almost the same. Reviews of each drug can be found on the Internet. However, there is a slight difference in price. And in this case, Genale, whose price is about 250 rubles, is more profitable than Postinor with a cost of 350 rubles.
Special instructions for use
Tablets should not be taken as permanent contraception because they do not protect against STDs, including HIV and AIDS. After a single use of the tablets, it is necessary to use other methods of barrier contraception. Not recommended for too frequent use.
It is also necessary to understand that 10 mg of mifepristone is not enough for medical abortion, and before taking this drug, you need to make sure that you are not pregnant using highly sensitive tests.
Also, if an unwanted pregnancy still occurs after taking the pills, it is necessary to resort to surgical or medical abortions. If the girl decides to keep the fetus, it is impossible to predict health status of the unborn child. Mifepristone is known to adversely affect the fetus.
Take strictly using the instructions and after visiting the gynecologist.
Store tablets in a dry place, protected from bright light.
The drug is dispensed without a doctor's prescription.
Genale tablets: patient reviews
I never used the method of emergency contraception, but it turned out that I had to urgently take either Genale or Postinor. Chose Jenale. In principle, I did not feel any side effects.
Feedback from Vicki, 32 years old.
Always use protection if you don't want to get pregnant. In an emergency situation, Zhenale's tablet helped me, but it's better not to bring it to this.
Feedback from Nastya, 26 years old.
Used Genale to terminate a pregnancy on the recommendation of a doctor. There was bleeding, terrible pain, but still a miscarriage occurred. I think such side effects occur after any medical abortion, not necessarily with Genale.
Feedback from Ekaterina, 24 years old.
Genale is an antiprogestogen for internal use. In his chemical formula mifepristone, a steroid antiprogestogenic agent of synthetic origin, dominates, blocking the action of the hormone progesterone at the receptor level, while not possessing gestagenic activity.
Under the action of the Genale tablet, the excretion of the fetal egg is observed, which entails a change in the endometrium, a noticeable inhibition of ovulation and an obstacle to the implantation of a fertilized egg.
The maximum plasma concentration is noticeable after about an hour, and the half-life is 18 hours.
Excipients are lactose monohydrate, potato starch, povidone, sodium carboxymethyl starch and magnesium stearate.
Genele is produced in the form of round yellow tablets with a green tint.
Among the analogues, Postinor is known.
Indications and contraindications for the use of Genale
The use of Genale is appropriate if you need urgent contraception after unprotected or unplanned intercourse, but no later than 72 hours.
The list of contraindications is quite capacious, so it is better to read the instructions before using the tablets. So, taking Genale is not indicated for pathologies of the kidneys and liver, porphyria, anemia, adrenal insufficiency, pregnancy, lactation, as well as long-term therapy with glucocorticosteroid drugs. Also, restrictions apply to patients who experience hypersensitivity to the components of this contraceptive.
Side effects and overdose of Genale
Side effects after applying Genale can affect many vital important systems. So, in the reproductive system, blood discharge from the vagina, discomfort and pain in the lower abdomen, as well as an exacerbation of the pathological processes of the appendages and uterus are possible. Indigestion is accompanied by nausea, vomiting and diarrhea, and CNS disorders are represented by dizziness and migraine attacks. In addition, in some clinical pictures there are allergic reactions on the skin, in particular, urticaria, itching and swelling.
In cases of overdose of Genale, adrenal insufficiency may predominate.
Instructions for use Genale
The drug is taken orally. One tablet of Genale inside two hours or two hours after the usual meal, but no later than 72 hours after sex.
Features of the use of Zhenale tablets
Taking the drug does not depend on the menstrual cycle.
Genale does not protect against sexually transmitted diseases or AIDS.
This contraceptive is not a method of permanent contraception, and it is indicated to take it only in emergency cases. Cannot be taken monthly or multiple times at a time menstrual cycle.
In the future, choose a more reliable contraceptive for regular use.
In the event of the ineffectiveness of Zhenale's tablets and the onset of pregnancy, it is necessary to terminate it with a surgical or medical method. If you want to keep the pregnancy, the risk of pathological development of the fetus increases, and the child will be born with serious pathologies.
The influence of Genale on the management of vehicles and other mechanisms is not observed.
Store in a cool place and use as directed.
drug interaction. For 8-12 days after taking Genale, do not use NSAIDs, but otherwise there are no restrictions.
Reviews about the drug Zhenale, price
Of course, many patients prefer the Postinor medicine, which has been tested for decades, as an emergency contraception, but the popularity of Genale is also growing every day.
Captivating is the fact that Genale contains only one pill, which protects against pregnancy, while Postinor's intake includes two pills, which should be taken according to a certain scheme. There is only one conclusion: Genale is easy to use.
Reviews about Zhenal are extremely positive, since the drug is a real lifesaver after thoughtless sexual contact. It gives a 99% guarantee that pregnancy will not occur in the future.
There are no negative reviews regarding the uselessness of Genale. It is extremely rare to find notes on the detection of side effects that are limited solely to nausea and dizziness.
The use of Genale does not require specialist advice, but it still does not hurt to read the instructions carefully before taking it. The drug is really highly effective, so many women use it with confidence.
The price of Zhenale 10mg tablet x1 is 305 rubles
01:31 Genale: instructions, application, reviews -
Unprotected intercourse often leads to a highly unwanted pregnancy, which is not in the plans of many women. That is why many ladies know firsthand about the Genale pills, which provide emergency contraception. General Description of Genale Tablets Genale is an antiprogestogen drug for internal use. Its chemical formula is dominated by mifepristone, a steroid antiprogestogenic drug of synthetic origin, which blocks the action [...]
Content
If during sex, contraceptive methods were ineffective or were not used at all, in order to prevent unwanted pregnancy, it is recommended to take Genale. This is an emergency contraceptive drug, under the influence of which the endometrium becomes so weak and thin that a fertilized egg cannot attach to the walls of the uterus. The tool has many side effects, therefore, it should be used no more than once a month, having previously studied the instructions. For the same reason, the drug cannot be included in the planned contraceptive regimen.
Instructions for use Genale
Genele is produced by the Russian pharmaceutical company Izvarino Pharma. The active ingredient of the drug is the synthetic steroid mifepristone. This substance is used for:
- medical abortion in the first month and a half of pregnancy without surgery;
- to prevent conception after unprotected sex or when protection measures were ineffective (broken condom, missed the deadline for taking contraceptives, etc.)
Composition and form of release
Genale are yellow-green tablets that are produced in cartons or jars in the amount of 1 or 2 pcs. One capsule contains 10 mg of mifepristone, the dose needed to prevent a fertilized egg from implanting in the uterus. Additional components of the steroid agent are:
Excipients | Dose per tablet (mg) | Properties |
|---|---|---|
lactose monohydrate | consists of lactose with an attached water molecule, is a sweetener |
|
potato starch |
|
|
Povidone K25 | binds toxins |
|
sodium carboxymethyl starch (primogel) | thickener |
|
magnesium stearate | creates a homogeneous mass, promotes the restoration of the endocrine system |
Pharmacodynamics and pharmacokinetics
In the first phase of the menstrual cycle, mifepristone inhibits the development of the follicle, blocking the effect of the hormone progesterone on the reproductive system through receptors. For this reason, it is considered an antiprogestogen. The role of progesterone is that it is actively involved in the preparation of the female body for pregnancy, and after the onset of conception, it contributes to the bearing of the fetus.
A delay in the development of the follicle leads to a later onset of ovulation (the release of a mature egg from it), during which conception occurs. This allows you to prevent fertilization according to the calendar period. However, during subsequent sex during this menstrual cycle, protection should be used, since a woman can become pregnant due to the fact that ovulation occurred later and went unnoticed. For the same reason, the menstrual cycle is disrupted, which is why the next menstruation comes late.
Genale stops the implantation of a fertilized egg, increasing the contractility of the myometrium, the muscular layer of the uterus, and its sensitivity to prostaglandins. The agent stimulates the release of interleukin 8 in choriodecidual cells (formed during pregnancy), which activates the migration of immune cells to the infected site. All this leads to exfoliation of the decidua (the functional layer of the endometrium that separates the fetus from the myometrium) and the release of a fertilized egg.
The maximum level of mifepristone in the blood is observed one and a half hours after the use of the drug. In the bloodstream, 98% of the active ingredient binds to transport proteins that carry it to its destination. The withdrawal of the drug from the body is carried out in several stages: at first slowly, then the process is significantly accelerated. The half-life of the drug is 17 hours.
Indications for use
Genale is designed for emergency contraception after sex during which contraceptive methods were not used or they were ineffective. It should be noted that the United States and many European countries have banned the sale of drugs based on mifepristone as a means of preventing pregnancy, and are used only for medical abortion under the strict supervision of a physician.
Method of application and dosage
To prevent pregnancy, you need to drink 1 tablet of Genale 2 hours before or after meals, regardless of the phase of the menstrual cycle, for three days after unprotected sex. The sooner this is done, the greater the chance of preventing conception. If before that a woman had sexual intercourse, before taking the drug, you should do a pregnancy test by donating blood for hCG: if she is already expecting a baby, you can not take the drug. One tablet is not enough to provoke a miscarriage, and the body of the fetus will be harmed.
special instructions
Genale for abortion causes hormonal disruptions, changes in the structure of the myometrium, so you can not use it as a permanent method of contraception. During the menstrual cycle during which the pill was drunk, sex should be done using a barrier method of contraception. This will not only protect against unwanted pregnancy, but also prevent AIDS and other sexually transmitted diseases: pills are powerless against them.
If pregnancy occurs after Genale, doctors recommend an abortion, since the drug can cause serious pathologies and disability in the fetus. Nevertheless, there are many cases when women, after taking the drug, decided to give birth, and the child was born healthy. Laboratory and instrumental studies - blood tests, ultrasound, etc. will help to dispel or confirm fears during pregnancy.
drug interaction
Genale may reduce the effectiveness of drugs used to treat other conditions. For this reason, after taking Genale for two weeks, it is not recommended to use non-steroidal anti-inflammatory drugs. Among them:
- Acetylsalicylic acid, known under the brand name Aspirin;
- Indomethacin;
- ibuprofen;
- Citramon;
- Indomethacin;
- Metindol;
- Naproxen;
- Butadion;
- Reopirin.
Genale and alcohol
Alcohol reduces the effectiveness of the remedy. The interval between the last drink of alcohol and Genale should be 3 hours, while the amount of alcohol drunk should not exceed 20 mg of ethanol (50 g of wine, a glass of vodka, half a liter of beer). With the simultaneous intake of alcohol and Genale, the load on the liver and kidneys increases, which are responsible for processing toxins and removing them to the outside in the composition of feces or urine. This combination can lead to malfunctions of the gastrointestinal tract, which is manifested by diarrhea, vomiting, nausea.
Side effects of Genale
After taking Genale, many women have a severe menstrual cycle, the delay can be one to two months. Among the side effects are bloody discharge from the genital tract, pulling pain in the lower abdomen, dizziness, migraines, weakness. The drug can provoke an allergy in the form of a rash, itching, urticaria, etc. Possible hyperthermia (fever), nausea, diarrhea, exacerbation of chronic inflammation of the uterus and appendages.
Contraindications
Like any other medical drug, Genale has contraindications. These include:
- long-term treatment with glucocorticosteroids (the drug is their antagonist);
- porphyria - a violation of pigment metabolism with an increased content of porphins in the blood;
- hepatic, renal or adrenal insufficiency;
- anemia;
- failure;
- pregnancy, lactation;
- an allergic reaction to the components of the drug;
- violation of homeostasis;
- severe form of extragenital pathology.
Terms of sale and storage
Birth control pills Genale is sold by prescription. Store the product in a dry, dark place, protected from sunlight, at temperatures up to 25°C. Shelf life - 3 years from the date of manufacture.
Analogues
Genale can be replaced with another emergency contraceptive, which contains mifepristone at a dosage of 10 mg, and the main difference will be in the excipients. Such a drug is the Russian Ginepriston, the additional components of which are microcrystalline cellulose, sodium carboxymethyl starch, calcium stearate.
If the dose of mifepristone in a tablet exceeds 10 mg, the drug has a different purpose. For example, Ginestril, a tablet containing 50 mg of mifepristone, is used to treat uterine fibroids (benign tumors). Blocking progesterone receptors helps to inhibit tumor growth, reduce the uterus and myomatous nodes.
Preparations based on mifepristone at a dosage of 200 mg are used for medical abortion in the first month and a half of pregnancy and induction of labor in case of fetal death. The scheme of the drug is prescribed by the doctor based on individual indicators. To get rid of an unwanted pregnancy, the remedy should not be taken at your own peril and risk. These drugs include:
- Mifepristone (Russia);
- Mifegin (France);
- Mytholian (China);
- Mifepresk (Russia);
- Pencrofton (Russia);
- Miropriston (Russia).
Genale or Postinor - which is better
Contraceptive pills Zhenale can be replaced by the Hungarian drug Postinor, the active substance of which is levonorgestrel (0.75 mg per tablet). This is a synthetic progestogen hormone that reduces the level of FSH and LH, pituitary hormones, under the influence of which the egg matures, it exits the follicle, and the body prepares for fertilization and pregnancy.
After unprotected sex, Postinor should be taken twice: the first dose - within three days, then - after twelve hours. In this regard, Zhenale is a more convenient drug, the load on the kidneys and liver is lower. If a woman is undergoing treatment, you should be aware that the list of drugs not recommended for simultaneous use with Postinor is wider (antibiotics, antiviral drugs, tetracycline, sleeping pills). The advantage of Postinor is that if conception has occurred, it does not affect the pregnancy and does not harm the fetus.
Genale or Escapelle - which is better
An emergency contraceptive is the Hungarian drug Escapel, the active ingredient of which is levonorgestrel (1.5 mg per tablet). For the remedy to work, you need to drink 1 tablet within 72 hours. The effectiveness of the remedy is 84% on the first day, 65% on the second day, 45% on the third, while in Genale this indicator is more stable and almost does not change for three days. If pregnancy after taking Escapel, like Postinor, has occurred, the child can be saved.
Price
The drug Zhenale is sold in many pharmacies in Moscow and the Moscow region. The price ranges from 400 rubles.
Latin name: zhenale
ATX code: G03XB01
Active substance: mifepristone
Manufacturer: OOO Izvarino Pharma, Russia
Pharmacy leave condition: On prescription
Genele is a birth control pill that causes bleeding shortly after taking it. This is emergency contraception, the use of which is intended to quickly prevent a possible pregnancy.
Indications for use
A contraceptive is taken to prevent conception after unprotected sex or when another contraceptive method has proven unreliable. For termination of pregnancy, pills are not suitable for women. Birth control pills must be taken within 72 hours (three days) of the last unsafe sexual intercourse.
The composition of the drug
In tablets, the active substance mifepristone is contained in an amount of 10 mg per piece. Additionally, the composition of the drug includes such excipients: povidone, lactose monohydrate, magnesium stearate and potato starch.
Medicinal properties
How does the medication work?
The active substance based on mifepristone has a contraceptive and antiprogestogenic effect. Mifepristone refers to synthetic steroid hormones, the mechanism of action of which is antiglucocorticoid activity by a competitive mechanism. The effectiveness of the drug depends on the specific phase of the cycle when the woman took the pill. Thanks to the drug, the contractility of the myometrium is effectively increased, interleukin-8 is released in choriodecidual cells.
It also reduces sensitivity to prostaglandins. Because of this, the fetal egg does not attach to the wall of the uterus, if conception occurs, ovulation does not occur, and the endometrium becomes thinner. After oral administration, the drug is absorbed by 70% and reaches a peak concentration in the blood after an hour and a half. The elimination half-life averages 17 hours. It is excreted from the body completely within three days.
Release form
The average cost of a drug in Russia is 290 rubles per pack.
The instruction indicates that the drug looks like round and convex tablets on both sides. One package contains 1 or 2 pieces, color - yellow-green. They can be sold in packs or cans.
Mode of application
How to take the medicine:
The remedy can be drunk 2 hours after a meal or before, as food in the stomach impairs the absorption of the active substance. Before using the tablets, you should consult a gynecologist to understand whether mifepristone will help in a particular case, namely, to come after menstruation. To ensure the effect of the drug, it must be drunk within three days after unprotected sex.
How long does it take for the medicine to work?
The drug begins to act approximately 2 hours after ingestion, and over time, a possible interruption of conception occurs. If the remedy was taken during ovulation or in the first phase of the cycle, then a delay after the woman is possible. In the second phase, fast menstruation often occurs. Pregnancy after marriage most often occurs in obese women and those who took the required dosage late.
Genale or escapelle?
Escapelle consists of synthetic progestogens. It must be taken no later than 1-2 days after the completion of sexual intercourse. Perhaps a negative consequence of the use - the woman will be pregnant ectopically. Such a pregnancy must be terminated as early as possible, otherwise it is possible to get an ovarian rupture, and the fetus will not survive 100% in any case. What is better to choose? The first drug is recommended.
Genale or postinor?
Postinor consists of levonogestrel, a synthetic progestogen. In order for the drug to work well after a while, you should have as little body weight as possible, that is, it may not help large-sized women. There is always one negative effect - after the postinor, daub begins. This is bleeding, reminiscent of menstruation. Such unpleasant consequences are fraught with severe bleeding, which will begin suddenly and with severe pain.
Ginepriston or zhenale?
Ginepristone has the same active ingredient - mifepristone, so these are two identical analogues. Does ginepristone help or not and which one can be considered the best? The drugs work in the same way, but only a doctor prescribes medicines.
During pregnancy and breastfeeding
If a woman becomes pregnant and her period does not come, then mifepristone can be taken for medical abortion within 3-4 weeks after the start of the delay. This procedure can not be carried out independently, the dosage is prescribed by the doctor. If bleeding has begun, then after 1.5 - 2 days, funds based on prostaglandins are prescribed. After 1-2 months of pregnancy, a vacuum or surgical abortion is already performed.
Contraindications
Porphyria, liver and kidney disease, homeostasis, anemia, adrenal dysfunction, allergic reaction, desired pregnancy and lactation.
Precautionary measures
Cross-drug interactions
Genale and alcohol
It is not recommended to mix alcohol with the medicine, otherwise the side effects may worsen, the alcohol itself negatively affects the effectiveness of the medication. Also, you can not prick after taking the drug non-steroidal painkillers for 12 hours.
Side effects
Migraine, dizziness, allergic rash, loss of working capacity, diarrhea and vomiting, pain in the lower abdomen, spotting, fever.
Overdose
Possible hypofunction of the adrenal glands.
Terms and conditions of storage
Up to three years in a dry and cool place.
Analogues
ZAO Obninsk Chemical Pharmaceutical Company, Russia
average price- 2100 rubles per package.
Miropriston is a complete analogue for active substance but with a difference in concentration. One tablet contains 200 mg of mifepristone. Only 3 tablets in a pack. Miropristone is needed for medical abortion.
Pros:
- Efficiency
- Convenience of the release form.
Minuses:
- Expensive
- Causes severe discomfort.
Gedeon Richter, Hungary
average price in Russia - 390 rubles per pack.
Postinor contains a synthetic progestogen in large quantities - levonorgestrel, which causes a sharp cycle failure in order to prevent conception. The pack sells 2 tablets of 750 mg each, which you need to drink as quickly as possible.
Pros:
- Helps
- Relatively inexpensive.
Minuses:
- Severely disrupts the cycle
- Causes bleeding.
